Koutsogiannaki et al., Aquat Toxicol 2006
(Cadmium Poisoning) :
Incubation of gill cells with the oxidants rotenone, antimycin A and pyruvate caused a significant increase in pHi ( delta pHi 0.830, 0.272 and 0.610, respectively ), while in the presence of the anti-oxidant N-acetyl cysteine (NAC) a decrease in pHi ( delta pHi -0.090 ) was measured, indicating that change in reactive oxygen species ( ROS ) production by heavy metals affects NHE activity
Barbey et al., Free Radic Res Commun 1989
(Kidney Diseases) :
phi was not affected by NAC