Gene interactions and pathways from curated databases and text-mining

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GP1BB — GP9

Pathways - manually collected, often from reviews:

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Hayashi et al., Semin Thromb Hemost 2000 (Bernard-Soulier Syndrome) : Mutant GPIX could not increase surface expression of the GPIb/IX complex, thus demonstrating an important role of the LRR of the GPIX polypeptide during biosynthesis
López et al., Blood Coagul Fibrinolysis 1994 : Association of GP Ib with actin binding protein does not require GP IX ... GP IX is necessary for optimal expression of the GP Ib-IX complex on the surface of transfected cells, and presumably also on the surface of the platelet ... These data indicate that the association of GP Ib with the cytoskeleton is independent of GP IX , which therefore must increase surface expression of the complex by another mechanism