◀ Back to IL10
CRP — IL10
Text-mined interactions from Literome
Szalai et al., J Immunol 2002
(Encephalomyelitis, Autoimmune, Experimental) :
Human
CRP has three effects on cultured encephalitogenic cells that could contribute to the protective effect observed in vivo : 1 ) CRP inhibits encephalitogenic peptide induced proliferation of T cells ; 2 ) CRP inhibits production of inflammatory cytokines ( TNF-alpha, IFN-gamma ) and chemokines ( macrophage-inflammatory protein-1alpha, RANTES, monocyte chemoattractant protein-1 ) ; and 3 ) CRP
increases IL-10 production
Singh et al., Arterioscler Thromb Vasc Biol 2006
:
We tested the
effect of
CRP on lipopolysaccharide (LPS) induced
IL-10 secretion in human monocyte derived macrophages ( HMDMs ) ... Fc gamma receptor I antibodies significantly reversed
CRP mediated
IL-10 inhibition ... cAMP agonists reversed
CRP mediated
IL-10 inhibition
Haider et al., Clin Exp Immunol 2006
(Endotoxemia) :
LPS,
interleukin (IL)-1 , IL-6 and tumour necrosis factor (TNF)-alpha increased and IL-10
reduced CRP expression in PBMC
Peroś-Golubicić et al., Acta Med Iugosl 1991
(Lung Diseases...) :
It is well known that
interleukin-1 , among other functions,
stimulates the hepatic production of
C-reactive protein
Pepys et al., J Immunol Methods 2012
(Amyloidosis) :
Importantly, we demonstrate that, contrary to reports using recombinant proteins and less well characterized preparations, neither
CRP nor SAP stimulate the release by human peripheral blood mononuclear cells in vitro of any TNFa, IL-6 or IL-8, nor does SAP
cause release of IL-1ß or
IL-10
Mackiewicz et al., Biochem J 1988
:
While both
interleukin-1 and tumour necrosis factor regulate biosynthesis of a number of these acute phase proteins in rabbit primary hepatocyte cultures, neither of these monokines
induced C-reactive protein synthesis
Zhang et al., Biochem J 1995
:
The
effect of
interleukin-1 on
C-reactive protein expression in Hep3B cells is exerted at the transcriptional level
Ramani et al., FEBS Lett 1994
:
Interleukin-10 and pentoxifylline inhibit
C-reactive protein induced tissue factor gene expression in peripheral human blood monocytes