Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
TLR3 ▸ ICAM1 ▸ NM ▸ TLR5 ▸ PTGS2 ▸ CD40 ▸ IL13 ▸
VEGFA ▸ AHSA1 ▸ TLR9 ▸ TLR1 ▸ CA2 ▸ CCL2 ▸ TLR8 ▸
TLR7 ▸ IL3 ▸ RNF19A ▸ TLR6 ▸ IL15 ▸ TLR10 ▸ TGFB1 ▸
IL5 ▸ LTA ▸ IL33 ▸ TCF21 ▸ TCF4 ▸ NOS2 ▸ F2RL1 ▸
IL18 ▸ TCF19 ▸ TCF7 ▸ CRK ▸ TCF12 ▸ TCF20 ▸ TCF3 ▸
TCF23 ▸ TCF24 ▸ IL22 ▸ TCF25 ▸ TCF15 ▸ NFKBIA ▸ PIK3R1 ▸
CSE ▸ NA ▸ PIK3CA ▸ IL1RN ▸ LPA ▸ MMP9 ▸ IL32 ▸
LEO1 ▸ GRAP2 ▸ PAF1 ▸ APOB ▸ IL31 ▸ CTR9 ▸ HGF ▸
WDR61 ▸ CDC73 ▸ EGF ▸ IL7 ▸ IL11 ▸ IFNB1 ▸ MMP2 ▸
CXCR1 ▸ S100A8 ▸ IL16 ▸ ITGAM ▸ IL19 ▸ IL21 ▸ IL25 ▸
IL9 ▸ FGF2 ▸ IL20 ▸ IL27 ▸ SAA1 ▸ POLDIP2 ▸ FAS ▸
INS ▸ MMP3 ▸ IL34 ▸ IL24 ▸ IL37 ▸ IL26 ▸ MIF ▸
NOS1 ▸ EGFR ▸ AKT2 ▸ PI3 ▸ CRP ▸ AKT3 ▸ CXCR2 ▸
ALB ▸ AKT1 ▸ MMP13 ▸ CALM3 ▸ NOX1 ▸ MMP1 ▸ CD14 ▸
CASP3 ▸ CASP4 ▸ IKBKB ▸ CASP7 ▸ CASP12 ▸ F2R ▸ CASP1 ▸
CASP9 ▸ CASP14 ▸ CD40LG ▸ NOX4 ▸ CASP16 ▸ CASP2 ▸ CASP5 ▸
CASP6 ▸ NOS3 ▸ CASP8 ▸ CASP10 ▸ NOX3 ▸ PLG ▸ HMGB1 ▸
NOX5 ▸ PTX3 ▸ MYLIP ▸ PTK2 ▸ LIF ▸ TGFB2 ▸ ITGB2 ▸
TNFSF10 ▸ NOD1 ▸ PTK7 ▸ SELE ▸ MYD88 ▸ PTK6 ▸ IGF1 ▸
CHUK ▸ PRG3 ▸ MMP8 ▸ PTX4 ▸ STAT3 ▸ SRC ▸ MUC1 ▸
TREM1 ▸ IFNA2 ▸ GP2 ▸ MAP3K7 ▸ ERVK-6 ▸ PRG4 ▸ GP6 ▸
IL12B ▸ GP5 ▸ GP9 ▸ LEP ▸ CXCL12 ▸ PRG2 ▸ IKBKG ▸
HDAC2 ▸ SOD1 ▸ PRKACB ▸ PLD2 ▸ SOD2 ▸ PRKAR2B ▸ HNRNPF ▸
IFNA6 ▸ IFNA17 ▸ PRKAR1A ▸ IFNA7 ▸ S100A12 ▸ PRKACG ▸ IFNA4 ▸
IFNA10 ▸ MMP7 ▸ PTBP2 ▸ PRKAR2A ▸ IFNA5 ▸ PAM ▸ HNRNPH1 ▸
CSF3 ▸ IFNA14 ▸ MPO ▸ IL12A ▸ VCAM1 ▸ VIP ▸ WNK1 ▸
SOD3 ▸ IFNA16 ▸ IFNA8 ▸ SERPINE1 ▸ PTBP1 ▸ CRH ▸ IFNA1 ▸
MMP14 ▸ PRKAR1B ▸ IFNA13 ▸ IFNA21 ▸ LTB ▸ MMP11 ▸ MMP19 ▸
TGFB3 ▸ TNFRSF1A ▸ SETD2 ▸ MMP21 ▸ MMP10 ▸ EDN1 ▸ MMP20 ▸
ELANE ▸ MSH3 ▸ MMP26 ▸ NOD2 ▸ MMP16 ▸ CXCL10 ▸ FGF1 ▸
EGR1 ▸ CAT ▸ HDAC1 ▸ MMP27 ▸ MMP25 ▸ CCL3 ▸ PLD1 ▸
SPP1 ▸ MMP28 ▸ MMP12 ▸ MMP17 ▸ IL1R1 ▸ MMP15 ▸ CSK ▸
MMP24 ▸ PLA2G1B ▸ NAALADL1 ▸ MSH5 ▸ ANGPT2 ▸ SYT1 ▸ MSH4 ▸
TAB1 ▸ SST ▸ QRICH2 ▸ MSH6 ▸ PLD3 ▸ MAP2K1 ▸ FASLG ▸
PLD4 ▸ PLD6 ▸ TRAF6 ▸ FGF7 ▸ CD4 ▸ PLD5 ▸ MSH2 ▸
CD8A ▸ QRICH1 ▸ AHR ▸ ADIPOQ ▸ CD46 ▸ FGF13 ▸ PDLIM7 ▸
FGF20 ▸ HMOX1 ▸ STX2 ▸ FGF10 ▸ CD38 ▸ HDAC5 ▸ CD28 ▸
FGF14 ▸ FGF8 ▸ FGF4 ▸ FGF21 ▸ C1QB ▸ FGF9 ▸ TNFSF12 ▸
NGF ▸ CXCL1 ▸ P2RY6 ▸ CSRP1 ▸ FGF22 ▸ FGF5 ▸ HDAC6 ▸
SELP ▸ C1QA ▸ FGF18 ▸ FGF11 ▸ SAA2 ▸ HSPD1 ▸ TXN ▸
HDAC3 ▸ STAT1 ▸ FGF16 ▸ PPARG ▸ FGF3 ▸ SOCS3 ▸ FGF23 ▸
RAC1 ▸ CSF1 ▸ FGF12 ▸ SELL ▸ LTF ▸ ITGB1 ▸ FGF19 ▸
ETS1 ▸ FGF6 ▸ FGF17 ▸ CD8B ▸ HDAC8 ▸ SAA4 ▸ TNFSF13B ▸
RHOA ▸ PRTN3 ▸ MUC19 ▸ MTX1 ▸ NAP1L4 ▸ HSPB1 ▸ ST8SIA2 ▸
HSPG2 ▸ HDAC11 ▸ NPS ▸ GPI ▸ TNMD ▸ MUC16 ▸ MUC20 ▸
PLA2G4A ▸ PLAU ▸ MUC12 ▸ MUC22 ▸ AGTR2 ▸ STAT4 ▸ CFTR ▸
ANGPT1 ▸ HDAC4 ▸ CPOX ▸ PRKCD ▸ MUC7 ▸ MUC2 ▸ TAT ▸
TRPV1 ▸ MUC8 ▸ PF4 ▸ PDCD11 ▸ ITIH4 ▸ ECM2 ▸ APC ▸
RBBP4 ▸ MUC13 ▸ CR1 ▸ MUC4 ▸ MUC15 ▸ CXCR4 ▸ ANG ▸
PDGFB ▸ PPARA ▸ STX1A ▸ RBBP7 ▸ SETBP1 ▸ HDAC7 ▸ BCL3 ▸
CD79A ▸ HDAC9 ▸ MTOR ▸ HDAC10 ▸ RHO ▸ MUC6 ▸ CXCR3 ▸
MUC21 ▸ IL2RA ▸ HES1 ▸ CISH ▸ ECM1 ▸ MUC17 ▸ PRR13 ▸
NR0B1 ▸ MT4 ▸ PRR26 ▸ ROCK2 ▸ TFPI ▸ CHI3L1 ▸ PRR3 ▸
PAEP ▸ IBD3 ▸ TAC4 ▸ PGF ▸ IBD4 ▸ PRR19 ▸ NR4A2 ▸
PRKAA1 ▸ PRR5 ▸ PRR12 ▸ HBEGF ▸ SELPLG ▸ CALM2 ▸ PRR25 ▸
IL1R2 ▸ MT3 ▸ TAC3 ▸ TPO ▸ PRKCA ▸ PRR22 ▸ EMD ▸
RENBP ▸ HDC ▸ PGD ▸ PRR16 ▸ UTP18 ▸ FGG ▸ FGA ▸
MET ▸ ADAM11 ▸ IBD9 ▸ MPL ▸ PRDX2 ▸ RNASE3 ▸ MAP3K1 ▸
IBD8 ▸ HES6 ▸ ADAM17 ▸ IRAK1 ▸ SEA ▸ TAC1 ▸ ADCYAP1 ▸
PRR21 ▸ MUC5AC ▸ PKD1 ▸ ICOSLG ▸ DDIT3 ▸ ICAM3 ▸ PRR9 ▸
IBD7 ▸ A2M ▸ IBD5 ▸ SMAD3 ▸ LPL ▸ PRR7 ▸ UTP15 ▸
HES7 ▸ EPO ▸ HES3 ▸ UTP3 ▸ IRAK3 ▸ ARG2 ▸ IL17F ▸
PRKAA2 ▸ CYP1A1 ▸ FOXO3 ▸ CXCL6 ▸ HES4 ▸ BCL10 ▸ ICAM2 ▸
TGFA ▸ AZU1 ▸ GRP ▸ SIGLEC7 ▸ MAP2K7 ▸ UTP20 ▸ IBD6 ▸
PTAFR ▸ DUSP1 ▸ UTP23 ▸ NTS ▸ APEX1 ▸ RELB ▸ PRR15 ▸
PRKAG2 ▸ ELF4 ▸ PRKAB1 ▸ PRL ▸ BRAF ▸ PRR11 ▸ ARG1 ▸
IFI44 ▸ PRR14 ▸ IBD2 ▸ PRKAG1 ▸ CTNNB1 ▸ OSM ▸ CCR5 ▸
CXCL11 ▸ ELF3 ▸ ICAM5 ▸ CALM1 ▸ TF ▸ BCL2 ▸ PRKAB2 ▸
FCGR1A ▸ PRR4 ▸ ETS2 ▸ UTP6 ▸ HES5 ▸ JAK2 ▸ HES2 ▸
PRR18 ▸ CCL20 ▸ NUP43 ▸ DEFA1 ▸ ICAM4 ▸ PRR24 ▸ TP53 ▸
CXCL9 ▸ CXCL17 ▸ ESR1 ▸ S100A9 ▸ FUT1 ▸ CXCL13 ▸ HCG25 ▸
CTSB ▸ GRB14 ▸ PITX1 ▸ HCG14 ▸ ARSA ▸ TRNAI1 ▸ PINK1 ▸
FUT4 ▸ ITGA5 ▸ IRS1 ▸ CYP19A1 ▸ FOXP3 ▸ DNASE1 ▸ CAPN15 ▸
ADAM10 ▸ FUT9 ▸ TACR1 ▸ SPP2 ▸ FXYD1 ▸ MEPE ▸ ALX1 ▸
PTPN11 ▸ ANPEP ▸ ASIP ▸ CD69 ▸ ALOX5 ▸ BMP2 ▸ NR4A1 ▸
GRB2 ▸ CAPN1 ▸ MAP2K4 ▸ CX3CL1 ▸ CTGF ▸ PROK1 ▸ NFKBIZ ▸
CAPN2 ▸ CAPN14 ▸ MYO6 ▸ CTSS ▸ KRT10 ▸ CPB1 ▸ HCG16 ▸
NPY6R ▸ SMAD5 ▸ ACKR3 ▸ DPM2 ▸ WNT2 ▸ HCG26 ▸ CNR1 ▸
PAH ▸ CAPN7 ▸ THBD ▸ SERPINB2 ▸ FOSL1 ▸ HCG4 ▸ FUT8 ▸
TNFRSF1B ▸ FMR1 ▸ HCG15 ▸ CAPN5 ▸ OXA1L ▸ HCG20 ▸ WNT1 ▸
CSH2 ▸ GAL ▸ PARK2 ▸ FUT2 ▸ TMSB4X ▸ AREG ▸ TNP2 ▸
ELAVL1 ▸ VDR ▸ NAMPT ▸ GRB7 ▸ MAP2K3 ▸ GRPR ▸ DUOX1 ▸
HCG23 ▸ CNR2 ▸ CAPN9 ▸ HCG9 ▸ KDR ▸ CXCL16 ▸ DNASE2 ▸
BCR ▸ HMGB3 ▸ GIP ▸ C1orf228 ▸ CXCL2 ▸ CXCL5 ▸ ELF2 ▸
TEC ▸ AR ▸ FOXO4 ▸ HCG11 ▸ MAP2K5 ▸ CEBPB ▸ MKNK1 ▸
MAP2K2 ▸ VAV1 ▸ PAK7 ▸ BPI ▸ ROCK1 ▸ CAPN13 ▸ APOE ▸
APOA1 ▸ TBP ▸ CDH1 ▸ PTHLH ▸ FCER2 ▸ NPY ▸ WNT6 ▸
PAK3 ▸ MRXS5 ▸ KLK3 ▸ CD83 ▸ FOXO6 ▸ FUT6 ▸ GH1 ▸
HCG22 ▸ SMAD4 ▸ GHRH ▸ CD86 ▸ IFIH1 ▸ FGB ▸ ELF5 ▸
ALX3 ▸ CSTA ▸ ATP8A2 ▸ PDGFA ▸ FUT5 ▸ HRH1 ▸ HMGB4 ▸
KLRB1 ▸ CAPN8 ▸ DEFA1B ▸ SMAD7 ▸ CAPN3 ▸ CAPN10 ▸ RNASE2 ▸
PAK6 ▸ TNPO1 ▸ MYO19 ▸ KSR2 ▸ DPM3 ▸ CSH1 ▸ RETN ▸
SMAD6 ▸ GSTM1 ▸ CYP1A2 ▸ PARK7 ▸ ADM ▸ CP ▸ RABEPK ▸
SMAD2 ▸ CEACAM1 ▸ WNT11 ▸ PAK1 ▸ CGN ▸ ELF1 ▸ RAC2 ▸
HRAS ▸ PGP ▸ MTA1 ▸ CAPN11 ▸ IL23A ▸ HBD ▸ MYO16 ▸
HCG24 ▸ ADAM19 ▸ TNFSF11 ▸ AGTR1 ▸ FOXO1 ▸ LBP ▸ JAK1 ▸
SMAD1 ▸ MTA2 ▸ CEACAM6 ▸ APOA2 ▸ HCG21 ▸ CXCL14 ▸ RAG1 ▸
CAPN12 ▸ WNT16 ▸ HCG8 ▸ WNT4 ▸ CD163 ▸ STAT5A ▸ BCL6 ▸
F7 ▸ FUT3 ▸ JAK3 ▸ F2RL2 ▸ IGF2 ▸ PAK4 ▸ DDX58 ▸
CD44 ▸ TNP1 ▸ MYO10 ▸ SOAT1 ▸ FUT10 ▸ FCGR2B ▸ CD2 ▸
HCG27 ▸ IDO1 ▸ CAPN6 ▸ PTPN22 ▸ CXCR6 ▸ HLA-DRB1 ▸ CCL4 ▸
TRAF2 ▸ FGFR2 ▸ CXCL3 ▸ MEFV ▸ HMGB2 ▸ ABL1 ▸ SERPINE2 ▸
WNT3 ▸ BLM ▸ NPY4R ▸ HCG17 ▸ CPB2 ▸ HIF1A ▸ MAP2K6 ▸
PAK2 ▸ VASP ▸ MPG ▸ UCN2 ▸ PTGS1 ▸ TPT1 ▸ PDCD4 ▸
VCP ▸ SCARB1 ▸ REL ▸ FUT7 ▸ SFXN1 ▸ CA1 ▸ SPESP1 ▸
TNFRSF9 ▸ FUT11 ▸ C3 ▸ CEBPA ▸ GRB10 ▸ POU2F1 ▸ RAC3 ▸
MBP ▸ CD1D ▸ SYK ▸ NLRP3 ▸ DPM1 ▸ CDH5 ▸ MAPKAPK2 ▸
CCL5 ▸ SLPI ▸ GAST ▸ SMAD9 ▸ TSC22D3 ▸ CDC42 ▸ ALX4 ▸
HCG18 ▸ F10 ▸ MTA3 ▸ SSTR5 ▸ TAS2R60 ▸ MT-RNR2 ▸ BDKRB2 ▸
TAS2R16 ▸ DRD2 ▸ NMU ▸ GNAI3 ▸ PDYN ▸ P2RY13 ▸ PTGER3 ▸
HCAR3 ▸ DRD4 ▸ HTR5A ▸ CCR2 ▸ P2RY12 ▸ U2AF1 ▸ PENK ▸
TAS2R5 ▸ TAS2R1 ▸ CCR10 ▸ S1PR1 ▸ XCR1 ▸ MCHR2 ▸ NPB ▸
GRM3 ▸ GNAT3 ▸ GALR3 ▸ MTNR1A ▸ ADORA3 ▸ TAS2R45 ▸ ADORA1 ▸
KNG1 ▸ GNG2 ▸ INSL5 ▸ HEBP1 ▸ NPY2R ▸ CCL28 ▸ CCR4 ▸
TAS2R31 ▸ HTR1E ▸ NPBWR2 ▸ GPER1 ▸ P2RY4 ▸ MCHR1 ▸ PPBP ▸
ANXA1 ▸ HRH3 ▸ NPY5R ▸ MTNR1B ▸ TAS2R3 ▸ RXFP3 ▸ CCR8 ▸
CHRM2 ▸ OPRL1 ▸ HTR1B ▸ TAS2R10 ▸ TAS2R41 ▸ CCR9 ▸ ADRA2A ▸
GABBR2 ▸ SSTR2 ▸ SUCNR1 ▸ OPRD1 ▸ CX3CR1 ▸ TAS2R39 ▸ ADRA2C ▸
HCAR2 ▸ SSTR3 ▸ GNAI1 ▸ HTR1D ▸ OXGR1 ▸ GRM4 ▸ FPR1 ▸
TAS2R19 ▸ PTGDR2 ▸ GNB1 ▸ APLNR ▸ S1PR3 ▸ GALR1 ▸ TAS2R13 ▸
PYY ▸ GNAI2 ▸ GRM2 ▸ HTR1A ▸ HTR1F ▸ TAS2R50 ▸ TAS2R14 ▸
GALR2 ▸ TAS2R7 ▸ CCR7 ▸ PNOC ▸ CCL19 ▸ S1PR5 ▸ SSTR4 ▸
LPAR5 ▸ DARC ▸ TAS2R38 ▸ TAS2R30 ▸ OPRK1 ▸ GRM6 ▸ CCL16 ▸
TAS2R43 ▸ SSTR1 ▸ PPY ▸ S1PR2 ▸ FPR3 ▸ NPY1R ▸ OXER1 ▸
TAS2R9 ▸ CCL25 ▸ TAS2R4 ▸ HCAR1 ▸ GRM8 ▸ DRD3 ▸ TAS2R20 ▸
CCR1 ▸ BDKRB1 ▸ CCL27 ▸ NMUR1 ▸ CCR6 ▸ PMCH ▸ TAS2R40 ▸
TAS2R42 ▸ C3AR1 ▸ S1PR4 ▸ NMUR2 ▸ TAS2R46 ▸ GRM7 ▸ TAS2R8 ▸
CHRM4 ▸ ADRA2B ▸ GABBR1 ▸ C5AR1 ▸ NPBWR1 ▸ HRH4 ▸ RXFP4 ▸
Data information
Please see the Gene Interactions Track Manual.