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IL15 — IL8

Text-mined interactions from Literome

Lügering et al., Immunology 1999 : Interleukin-15 strongly inhibits interleukin-8 and monocyte chemoattractant protein-1 production in human colonic epithelial cells ... We explored the regulatory effects of IL-15 on IL-8 and monocyte-chemoattractant protein-1 ( MCP-1 ) production in the colonic epithelial cell line Caco-2 as well as in freshly isolated human colonic epithelial cells ... These results show that IL-15 can suppress IL-8 and MCP-1 secretion by intestinal epithelial cells
Lottaz et al., J Invest Dermatol 2001 : We hypothesize that inhibition of this pathway prevents secretion of interleukin-1, thereby downregulating interleukin-1 dependent autocrine induction of interleukin-8
d'Ettorre et al., AIDS 2002 (HIV Infections) : The following parameters were evaluated : the production of IL-15 by peripheral blood mononuclear cells ( PBMC ) stimulated with lipopolysaccharide, Candida albicans and Mycobacterium avium complex ; the ability of IL-15 to induce the secretion of IL-8 and monocyte chemotactic protein-1 (MCP-1) from HIV positive monocytes ; and the virological effect of IL-15 and IL-2 on HIV replication in mononuclear cells
Prause et al., Eur J Pharmacol 2003 : Pharmacological modulation of interleukin-17 induced GCP-2-, GRO-alpha- and interleukin-8 release in human bronchial epithelial cells ... We found that interleukin-17 ( 1-1000 ng/ml ) increased the release of GCP-2, GRO-alpha and interleukin-8 in a concentration dependent manner
Waehre et al., J Am Coll Cardiol 2003 (Coronary Artery Disease) : Our main findings were : 1 ) gene expression of several chemokines ( i.e., macrophage inflammatory protein [MIP ] -1alpha, MIP-1beta, and interleukin [ IL]-8 ) and chemokine receptors ( i.e., CC chemokine receptor [ CCR]1, CCR2, CCR4, and CCR5 ) was markedly increased among CAD patients compared with healthy control subjects ; 2 ) treatment with atorvastatin and simvastatin markedly reduced the mRNA levels of some of these chemokines ( i.e., MIP-1alpha, MIP-1beta, IL-8 ) and receptors ( i.e., CCR1 and CCR2 ), with the most pronounced effect in the atorvastatin group ; and 3 ) statin therapy reduced the spontaneous release of IL-8 and MIP-1alpha from PBMCs in CAD patients
Winn et al., J Infect Dis 2003 : Selective effects of interleukin (IL)-15 on antifungal activity and IL-8 release by polymorphonuclear leukocytes in response to hyphae of Aspergillus species
Vittori et al., J Allergy Clin Immunol 1992 : Protective effect of nedocromil sodium on the interleukin-1 induced production of interleukin-8 in human bronchial epithelial cells
Uchiyama et al., Am J Obstet Gynecol 1992 : These results indicate that interleukin-8-like chemotactic factor participates in the cervical ripening at term pregnancy and that the production of this factor is controlled effectively by interleukin-1
Soloff et al., Endocrinology 2004 : In situ analysis of interleukin-1 induced transcription of cox-2 and il-8 in cultured human myometrial cells
Wuyts et al., J Heart Lung Transplant 2004 : N-acetylcysteine inhibits interleukin-17 induced interleukin-8 production from human airway smooth muscle cells : a possible role for anti-oxidative treatment in chronic lung rejection ?
Budagian et al., J Biol Chem 2004 (Prostatic Neoplasms) : Furthermore, stimulation of transmembrane IL-15 also enhanced the transcription of IL-6 and IL-8 in the PC-3 cell line and promoted migration of PC-3 cells as well as LNCaP human prostate carcinoma cells stably expressing IL-15 on the cell surface
Ozawa et al., J Immunol 2004 (Periodontitis) : Exogenous IL-2 and IL-15 induced production of MCP-1 but not IL-8 in normal HGF, and induced the production of both chemokines in inflamed HGF
D'Agostino et al., Scand J Immunol 2004 (Leishmaniasis, Visceral) : Interleukin-15 , as interferon-gamma, induces the killing of Leishmania infantum in phorbol-myristate-acetate activated macrophages increasing interleukin-12
Winn et al., Cytokine 2005 : IL-15 increased interleukin-8 (IL-8) release from PMNLs challenged with hyphae of F. solani and S. prolificans ( P < or = 0.04 )
Hirota et al., Rheumatol Int 1992 : Production of interleukin 8 by cultured synovial cells in response to interleukin 1 and tumor necrosis factor
Hashmi et al., Coron Artery Dis 2006 (Angina, Unstable) : Role of interleukin-17 and interleukin-17 induced cytokines interleukin-6 and interleukin-8 in unstable coronary artery disease
Tavian et al., Cytokine 2008 (Paracoccidioidomycosis) : In contrast, IL-8 and TNF-alpha levels were not affected by IL-15 suggesting that its effects were not mediated by these cytokines
Darbonne et al., J Clin Invest 1991 : Their binding of IL-8 is rapidly reversible and does not result in receptor internalization, although bound IL-8 is resistant to extraction by pH 3 buffer at 5 degrees C. 125I-IL-8 binding to red cells was not inhibited by epidermal growth factor or interleukin 1, but was inhibited by monocyte chemotactic peptide-1, which is not a neutrophil chemotaxin, but is a member of the same family of polypeptides as IL-8
Larsen et al., Biochem Biophys Res Commun 1991 : 1,25 ( OH ) 2-D3 is a potent regulator of interleukin-1 induced interleukin-8 expression and production
Hua et al., Molecular oral microbiology 2010 (Periodontal Diseases) : Furthermore, as little as 2 µg ml(-1) mPE was sufficient to inhibit interleukin-1ß induced secretion of interleukin-8 in both gingival epithelial cells and THP-1 cells
Vindeløv et al., Growth Horm IGF Res 2011 (Adenoma...) : Interleukin-8 production from human somatotroph adenoma cells is stimulated by interleukin-1ß and inhibited by growth hormone releasing hormone and somatostatin
Strieter et al., Am J Respir Cell Mol Biol 1990 : The induction of AMO derived IL-8 by tumor necrosis factor (TNF), lipopolysaccharide (LPS), and interleukin-1 ( IL-1 beta ) was shown to be both dose and time dependent
Ng et al., J Biol Chem 1994 : Although tumor necrosis factor (TNF) and interleukin-1 ( IL ) induce the expression of the IL-8 , TNF stimulated gene 6, and plasminogen activation inhibitor-2 genes and the activation of NF-kappa B with nearly identical kinetics, the two cytokines differ significantly in the induction of the IL-6 gene in all primary fibroblasts tested
Badolato et al., Blood 1997 (Inflammation) : Interleukin-15 (IL-15) induces IL-8 and monocyte chemotactic protein 1 production in human monocytes ... In addition, IL-8 and MCP-1 induction by IL-15 is differently regulated by interferon-gamma (IFN-gamma) and IL-4 ... IFN-gamma inhibited IL-15 induced IL-8 secretion, but synergized with IL-15 in MCP-1 induction ; whereas IL-4 inhibited both IL-8 and MCP-1 induction by IL-15
Krakauer et al., J Infect Dis 1998 : Interleukin-8 production by human monocytic cells in response to staphylococcal exotoxins is direct and independent of interleukin-1 and tumor necrosis factor-alpha
McDonald et al., Blood 1998 : Interleukin-15 (IL-15) induces NF-kappaB activation and IL-8 production in human neutrophils ... In particular, neutrophils synthesize and release IL-8 in response to IL-15 , but not to IL-2