Gene interactions and pathways from curated databases and text-mining

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CSF2 — TGFB1

Text-mined interactions from Literome

Chegini et al., J Clin Endocrinol Metab 1999 (Leiomyoma...) : Regulation of transforming growth factor-beta1 expression by granulocyte macrophage-colony stimulating factor in leiomyoma and myometrial smooth muscle cells
Zermati et al., Exp Hematol 2000 : When UT-7 cells were switched from GM-CSF to Epo, TGF-beta1 ( 2 ng/mL ) induced a rapid ( 3 days [ Epo+TGF-beta1 ] vs 8 days [ Epo ] ) and marked erythroid differentiation ( 80 % [ Epo+TGF-beta1 ] vs 10 % [ Epo ] BPC ) including Hemoglobin A synthesis ( HbA/HbF ratio of 1 [ Epo ] vs 4 [ Epo+TGF-beta1 ] )
Seppänen et al., Eur J Endocrinol 2000 (Cystadenocarcinoma...) : Similarly, GM-CSF induced a slight inhibition ( P < 0.05 ), whereas TGF-beta1 and TNF-alpha almost blocked DNA synthesis ( P < 0.001 ) after 72h
Ripley et al., Gynecol Oncol 2001 (Endometrial Neoplasms) : The effect of GM-CSF on DNA synthesis, cell proliferation, expression of GM-CSF, TGF-beta1 , and TGF-beta receptor, and their regulation by ovarian steroids was determined by the rate of [ ( 3 ) H ] thymidine incorporation, MTT assay, Q-RT-PCR, and ELISA, respectively
Xiao et al., Brain Behav Immun 2002 : In sharp contrast, TGF-beta 1 , in the presence of GM-CSF , dramatically up-regulated the expression of TNF-alpha and TGF-beta 1 mRNA
Swirski et al., Eur J Immunol 2004 (Eosinophilia) : Concomitant airway expression of granulocyte-macrophage colony stimulating factor and decorin, a natural inhibitor of transforming growth factor-beta , breaks established inhalation tolerance
Kaygusuz et al., Life Sci 2006 : In this study, the effects of the NSAID naproxen sodium, G-CSF , and both of them in combination on the TGF-beta1 serum level in rats with tibia fractures were measured and fracture healing was evaluated by histopathologic and radiologic examination
Lotem et al., Blood 1990 (Leukemia, Myeloid) : TGF-beta 1 suppressed the production of IL-6 in normal bone marrow cells cultured with IL-1 alpha and the production of IL-6 and GM-CSF in leukemic cells cultured with IL-1 alpha or LPS
Bellone et al., J Immunol 1995 : Exogenous bioactive TGF-beta 1 inhibited NK cell DNA synthesis and production of IFN-gamma, TNF-alpha, and granulocyte-macrophage CSF (GM-CSF) by NK cultures consisting of > 98 % CD56+ cells
Rosenfeld et al., Stem Cells 1994 : Transforming growth factor-beta 1 augments macrophage-colony stimulating factor activity on human marrow
Jacobsen et al., J Immunol 1993 : TGF-beta 1 up-regulated granulocyte-macrophage (GM)-CSF receptor expression in a time- and dose dependent manner, with a maximum up-regulation of 64 % by 48 h at 20 ng/ml
Hestdal et al., Exp Hematol 1993 : First, TGF-beta 1 enhanced the specific binding of GM-CSF ( 2.0-fold ) on bone marrow cells, reaching a maximum 40 hours after injection, while the specific binding of interleukin-3 (IL-3) was unaffected
Hong et al., J Immunol 1997 : Hydrogen peroxide mediated transcriptional induction of macrophage colony stimulating factor by TGF-beta1
Wu et al., J Surg Res 1997 (Ischemia...) : Macrophage colony stimulating factor accelerates wound healing and upregulates TGF-beta1 mRNA levels through tissue macrophages
Tremellen et al., Biol Reprod 1998 (Inflammation) : Seminal transforming growth factor beta1 stimulates granulocyte-macrophage colony stimulating factor production and inflammatory cell recruitment in the murine uterus
Crane et al., Clin Exp Immunol 1999 : IL-1beta, tumour necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta ( TGF-beta ) all stimulated GM-CSF production by RPE cells and a combination of these cytokines increased GM-CSF production over five-fold compared with that with the individual cytokines alone