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EMD — TGFB1
Text-mined interactions from Literome
Okubo et al., J Periodontal Res 2003
:
A purpose of this study is to determine
effects of
EMD on cell growth, osteoblastic differentiation and insulin-like growth factor-I (IGF-I) and
transforming growth factor-beta 1 ( TGF-beta 1 ) production in human periodontal ligament cells ( HPLC )
Rodrigues et al., J Clin Periodontol 2007
:
EMD induced PDL fibroblast proliferation and migration, total protein synthesis, ALP activity, and mineralization, while
TGF-beta1 increased cellular adhesion
Dacy et al., Int J Oral Maxillofac Implants 2007
:
EMD initiated early
TGF-beta1 production, but production decreased to control levels within 10 days
Patsenker et al., Gastroenterology 2008
(Cholestasis...) :
The
effect of
EMD527040 on cholangiocyte adhesion, proliferation, apoptosis, and
TGF-beta1 activation was studied in vitro
Messenger et al., J Tissue Eng Regen Med 2010
:
Additionally, it was shown that
EMD enhanced
TGFbeta1 synthesis of synovial cells, suggesting a potential mode of action for EMD 's capacity to stimulate tissue regeneration