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ETS1 — PARP9
Text-mined interactions from Literome
Soldatenkov et al., Oncogene 1999
(Sarcoma, Ewing) :
The
participation of
ETS in the regulation of
PARP gene expression was further demonstrated in EWS cells stably transfected with Ets1 antisense cDNA constructs ... Antisense mediated down-regulation of endogenous
ETS1 resulted in the inhibition of
PARP expression in EWS cells, and sensitized these cells to ionizing radiation ... These data provide support for
ETS regulation of
PARP expression levels, and implicate ETS transcription factors in the radiation response of EWS cells
Soldatenkov et al., Oncogene 2002
(Sarcoma, Ewing) :
Previously, we cloned the PARP gene promoter region from EWS cells, showed that it contained multiple ETS binding sites and demonstrated a positive
regulation of
PARP by
ETS1