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COQ5 — INS
Text-mined interactions from Literome
MacDonald et al., Biosci Rep 1991
:
CoQ6 and
CoQ10 ( ubiquinone ), duroquinone and durohydroquinone did not
stimulate insulin release ... Inhibitors of mitochondrial respiration ( rotenone, antimycin A, FCCP and cyanide ) and the calcium channel blocker verapamil, did not inhibit
CoQ0 induced
insulin release ... Dicumarol, an inhibitor of quinone reductase, did not inhibit
CoQ0 induced
insulin release, but it did inhibit glucose induced insulin release suggesting that the enzyme and quinones play a role in glucose induced insulin release
Kunitomo et al., J Pharmacol Sci 2008
(Body Weight...) :
CoQ10 prevented the elevated serum
insulin levels, although it did not affect the elevated glucose level and dyslipidemia