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Chen et al., Antioxid Redox Signal 2011
:
Hsp90 regulates NADPH oxidase activity and is necessary for superoxide but not hydrogen peroxide production
Chen et al., Arterioscler Thromb Vasc Biol 2012
:
Hsp90 inhibitors did not alter Nox5 micro RNA levels, and proteasome inhibition prevented Nox2 and 5 protein degradation and increased ubiquitin incorporation ... We conclude that Hsp90 binds to and regulates Nox protein stability