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IL17F — IL8
Text-mined interactions from Literome
Kawaguchi et al., J Allergy Clin Immunol 2006
(Asthma...) :
Furthermore, the H161R variant blocked
induction of
IL-8 expression by wild-type
IL-17F
Yagi et al., J Gastroenterol 2007
(Colitis) :
IL-17A and
IL-17F significantly
enhanced IL-6,
IL-8 , LIF, MMP-1, and MMP-3 secretion ... Both IL-17A and
IL-17F augmented IL-1beta induced secretion of IL-6,
IL-8 , LIF, MMP-1, and MMP-3 ... Inhibitors for ERK ( PD98059 and U0216 ) and p38 MAPK ( SB203580 ) significantly reduced the
IL-17F induced IL-6,
IL-8 , LIF, MMP-1, and MMP-3 secretion
Watanabe et al., J Invest Dermatol 2009
(Psoriasis) :
The results showed that
IL-17F induced production of
IL-8 in NHEKs in a time dependent manner ... Next, we confirmed that selective mitogen activated protein kinase kinase inhibitors significantly inhibited
IL-17F induced
IL-8 production ... These results indicate that
IL-17F may be
involved in psoriasis via, in part, the activation of ERK1/2 and the induction of
IL-8 in keratinocytes