Gene interactions and pathways from curated databases and text-mining

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IL17F — IL8

Text-mined interactions from Literome

Kawaguchi et al., J Allergy Clin Immunol 2006 (Asthma...) : Furthermore, the H161R variant blocked induction of IL-8 expression by wild-type IL-17F
Yagi et al., J Gastroenterol 2007 (Colitis) : IL-17A and IL-17F significantly enhanced IL-6, IL-8 , LIF, MMP-1, and MMP-3 secretion ... Both IL-17A and IL-17F augmented IL-1beta induced secretion of IL-6, IL-8 , LIF, MMP-1, and MMP-3 ... Inhibitors for ERK ( PD98059 and U0216 ) and p38 MAPK ( SB203580 ) significantly reduced the IL-17F induced IL-6, IL-8 , LIF, MMP-1, and MMP-3 secretion
Watanabe et al., J Invest Dermatol 2009 (Psoriasis) : The results showed that IL-17F induced production of IL-8 in NHEKs in a time dependent manner ... Next, we confirmed that selective mitogen activated protein kinase kinase inhibitors significantly inhibited IL-17F induced IL-8 production ... These results indicate that IL-17F may be involved in psoriasis via, in part, the activation of ERK1/2 and the induction of IL-8 in keratinocytes