Gene interactions and pathways from curated databases and text-mining

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CD28 — TAT

Text-mined interactions from Literome

Firpo et al., AIDS Res Hum Retroviruses 1992 (Simian Acquired Immunodeficiency Syndrome) : Whereas Nef can reduce expression of CD4, Tat reduces the expression of CD28
Ott et al., J Immunol 1998 : The effect of Tat101 on CD28REs in the IL-8 promoter and the subsequent up-regulation of IL-8 secretion is likely to contribute to the immune dysregulation observed during HIV-1 infection