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HK2 — SREBF1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Gosmain et al., Diabetes 2004
:
These results demonstrate that
SREBP-1c is
involved in the effect of insulin on
HKII gene transcription and indicate that it is one of the mediators of insulin action on gene expression in human skeletal muscle
Gosmain et al., J Lipid Res 2005
:
Regulation of
SREBP-1 expression and transcriptional
action on
HKII and FAS genes during fasting and refeeding in rat tissues ... The concomitant measurement of SREBP-1a and SREBP-1c mRNA levels, of mature SREBP-1 protein abundance in nuclear extracts, and of SREBP-1 interaction with target promoters led to the conclusion that
SREBP-1 plays a major role in the response of FAS and
HKII genes to nutritional regulation in rodents