Mathy-Hartert et al., Osteoarthritis Cartilage 2008
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This work was designed to assess the effects of interleukin (IL)-1beta and IL-6 on the enzymatic activity and gene expression of SODs, CAT and GPX in bovine chondrocytes ... In parallel, IL-1beta markedly enhanced Mn SOD and GPX gene expressions, but decreased Cu/Zn SOD, EC SOD and CAT gene expressions
Crosby et al., Biochim Biophys Acta 1996
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Interleukin-1 beta also increased glutathione peroxidase and conjugated diene formation ; the latter increased enzyme activity dose-dependently suggesting a possible role for this oxidation product in the induction of glutathione peroxidase activity