Gene interactions and pathways from curated databases and text-mining

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IKBKB — TSC2

Pathways - manually collected, often from reviews:

  • NCI Pathway Database mTOR signaling pathway: IKK beta (IKBKB) → TSC1/TSC2 complex (TSC1-TSC2) (modification, collaborate)
    Lee et al., Cell 2007
    Evidence: mutant phenotype, assay, physical interaction
  • NCI Pathway Database mTOR signaling pathway: IKK beta (IKBKB) → TSC1/TSC2/IKK beta complex (TSC1-TSC2-IKBKB) (modification, collaborate)
    Lee et al., Cell 2007
    Evidence: mutant phenotype, assay, physical interaction
  • NCI Pathway Database mTOR signaling pathway: TSC1/TSC2 complex (TSC1-TSC2) → TSC1/TSC2/IKK beta complex (TSC1-TSC2-IKBKB) (modification, collaborate)
    Lee et al., Cell 2007
    Evidence: mutant phenotype, assay, physical interaction