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MMP1 — RAF1
Text-mined interactions from Literome
Westermarck et al., Mol Cell Biol 2001
(MAP Kinase Signaling System) :
The activation of the extracellular signal regulated kinase 1 ( ERK1 ) /ERK2 ( designated ERK1,2 ) pathway by oncogenic Ras, constitutively active
Raf-1 , or phorbol ester
resulted in potent stimulation of
MMP-1 promoter activity and mRNA expression
Pap et al., Arthritis Rheum 2004
(Arthritis, Rheumatoid) :
Immunohistochemistry was used to study the
effects of DN
c-Raf-1 on phosphorylated c-Jun and
matrix metalloproteinase 1 (MMP-1) in RASFs implanted into SCID mice
Izbicka et al., Anticancer Res 2005
(Breast Neoplasms...) :
R115777 +/- paclitaxel inhibited HDJ-2 farnesylation, up-regulated RhoB, transiently lowered ( P ) ERK/ERK and ( P ) Akt/Akt, reduced
Raf-1 and MEK and
inhibited secretion of VEGF and
MMP-1