Gene interactions and pathways from curated databases and text-mining

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KDR — TGFB1

Text-mined interactions from Literome

Minami et al., J Biol Chem 2004 : Taken together, the present study provides evidence for a novel association between Hex and GATA and suggests that transforming growth factor beta mediated repression of flk-1/KDR and vascular endothelial growth factor signaling involves the inducible formation of inhibitory Hex-GATA complexes
Lombardero et al., Pituitary 2006 : At 24 hours, EGF and TGFbeta1 induced a significant increase in both VEGF and Flk-1 expression
Ferrari et al., Proc Natl Acad Sci U S A 2006 : Inhibition of p38 ( MAPK ) blocks TGF-beta1 induced apoptosis, showing that VEGF/flk-1 mediated activation of p38 ( MAPK ) is required for TGF-beta1 induction of apoptosis
Mandriota et al., J Biol Chem 1996 : Immunoprecipitation and Western blot experiments demonstrated a decrease in Flk-1 protein expression, and TGF-beta 1 reduced flk-1 mRNA levels in a dose dependent manner