Ohba et al., Hokkaido Igaku Zasshi 2001
:
In 293T cells, Rap2 was regulated by the same set of guanine nucleotide exchange factors ( GEFs ) and GTPase activating proteins ( GAPs ) as those which regulated Rap1 Vuchak et al., Cell Adh Migr 2011
(Colonic Neoplasms) :
Overexpression of Rap1GAP in human colon cancer cells impaired Rap2 activity and the ability of cells to spread and migrate on collagen IV