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DUOX2 — STAT1

Text-mined interactions from Literome

Wu et al., J Biol Chem 2011 : Up-regulation and sustained activation of Stat1 are essential for interferon-gamma (IFN-gamma) induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines
Wu et al., J Immunol 2013 (Chronic Disease...) : We recently demonstrated that dual oxidase (Duox)2 , an NADPH oxidase essential for reactive oxygen species related, gastrointestinal host defense, is regulated by IFN-? mediated Stat1 binding to the Duox2 promoter in pancreatic tumor lines ... Induction of Duox2 expression by IFN-? and LPS may result from IFN-? related activation of Stat1 acting in concert with NF-?B related upregulation of Duox2