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SMAD3 — SPP1

Text-mined interactions from Literome

Hullinger et al., Exp Cell Res 2001 : While previous studies have indicated that specific DNA sequences are recognized by Smad complexes in several promoters, the role of Smad binding elements ( SBEs ) in activation of the OPN promoter by members of the TGFbeta superfamily has not been previously evaluated
Sowa et al., J Bone Miner Res 2002 : Moreover, Smad3 increased the levels of type I procollagen, osteopontin (OPN), and matrix Gla protein (MGP) mRNA in Northern blotting
Saika et al., Lab Invest 2007 : OPN is required for activation of Smad2/3 signal in an injured lens epithelium and lens cell EMT