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PARP10 — TNF
Text-mined interactions from Literome
Sharp et al., Inflammation 2001
(Inflammation) :
PARP inhibition with GPI 6150 blocked the IL-1beta mediated stimulation of both ICAM-1 and E-selectin expression, and
blocked TNF-alpha stimulation of ICAM-1 expression at 24 h
Los et al., Mol Biol Cell 2002
(Necrosis) :
Our results indicate that
TNF induces
PARP activation leading to ATP depletion and subsequent necrosis
Epperly et al., Exp Hematol 2003
:
The cell lines overexpressing MnSOD ( 1F2 or 2C6 ) displayed decreased radiation induced,
TNF-alpha induced, or IL-3 withdrawal
induced mitochondrial membrane permeability, caspase-3 and
PARP activation, and apoptosis
Virág et al., Med Sci Monit 2004
(Asthma...) :
The production of
TNF- alpha and IL-12, but not IL-5 or IL-13, was also
suppressed by
PARP inhibition
Murata-Ohsawa et al., Int J Mol Med 2004
:
As the molecular mechanism involved, we showed Delta-1 stimulation partially suppressed the sequential activation of caspase-8, caspase-3, and,
PARP induced by
TNF-alpha
Czapski et al., Neurochem Int 2013
(Inflammation) :
However,
PARP activity
had no effect on the mRNA level of COX-2,
TNF-a and NADPH oxidase in the hippocampus
Ha Thi et al., Biochim Biophys Acta 2013
(MAP Kinase Signaling System...) :
TNF-a and TGF-ß synergistically
induced the degradation of poly ( ADP-ribose ) polymerase (
PARP ) and caspase cascade activation
Sleijfer et al., Int J Cancer 1998
(Carcinoma, Small Cell...) :
Moreover, it was demonstrated that combining TNF with the poly-ADP-ribose polymerase ( PARP ) inhibitors 6-aminonicotinamide and 3-aminobenzamide did not affect TNF-sensitivity in GLC4 and GLC4-Adr350x, excluding a pivotal
role of
PARP in
TNF-resistance in these cell lines