de Koning et al., Blood 1998
:
Importantly, G-CSF mediated activation of Shc , p21Ras and the induction of c-myc were severely reduced by substitution of Y764
Ward et al., Biochim Biophys Acta 1998
:
In this report, we show rapid phosphorylation of Shc upon stimulation of NFS-60 cells with G-CSF , and inducible association of Shc and Grb2 with the G-CSF-R in these cells