Gene interactions and pathways from curated databases and text-mining

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ITGA5 — SHC1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: SHC1 → ITGA5 (increases)
    Evidence: A dominant negative form of Shc carrying phenylalanine permutations at both tyrosines involved in Grb2 binding inhibited the activation of Rac in HUVECs plated on fibronectin in complete SFM.