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ABCC6 — CASP3
Text-mined interactions from Literome
Terrisse et al., Biochim Biophys Acta 2002
(Leukemia) :
Furthermore, neither DNR or
Ara-C induced
caspase-8 activation
Kogoshi et al., Oncol Rep 2005
(Leukemia...) :
To investigate the possible molecular mechanism of the protective effect, the influence of Jagged1 on
Ara-C induced
activation of
caspase-3 and PARP, and dephosphorylation of NF-kappaB was examined in NB4 cells
Engelbrecht et al., J Mol Cell Cardiol 2005
(MAP Kinase Signaling System...) :
EPA ( 20microM ) and
ARA ( 20microM ) significantly
inhibited caspase-3 activation and PARP-cleavage and reduced the apoptotic index during reperfusion
Ibrado et al., Cancer Res 1996
:
Overexpression of Bcl-2 or Bcl-xL inhibits
Ara-C induced
CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells
Kim et al., Cancer Res 1997
:
High-dose
Ara-C ( HIDAC )
induces the cleavage and activity of caspase-3 (
CPP32beta/Yama/apopain ), resulting in the morphological and biochemical features of apoptosis ... In HL-60/neo cells, HIDAC induced progressive accumulation of cytochrome c in the cytosol, the decrease in deltapsi m, and the increase in reactive oxygen species were not inhibited by coculture with the tetrapeptide inhibitors of caspases that have been previously shown to inhibit
Ara-C induced cleavage and activity of
caspase-3 and apoptosis