Gene interactions and pathways from curated databases and text-mining

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BATF — FOS

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Williams et al., Eur J Immunol 2001 : Since the differential regulation of AP-1 activity is linked to key transitions in the developing immune system, our observations support a critical role for BATF in determining the overall level of AP-1 activity, and thus AP-1 target gene expression, in specific T cell subtypes
Deppmann et al., Biochem J 2003 : Phosphorylation of BATF regulates DNA binding : a novel mechanism for AP-1 ( activator protein-1 ) regulation
Zullo et al., J Immunol 2007 : Consistent with the sensitivity of NKT cells to BATF induced changes in AP-1 activity, we detect a full complement of AP-1 basic leucine zipper proteins in wild-type NKT cells isolated from the thymus, spleen, and liver, and show that AP-1 DNA binding activity and cytokine gene transcription are induced in NKT cells within a few hours of glycolipid Ag exposure
Li et al., Immunity 2012 (Autoimmune Diseases...) : We discovered that Egr2 and/or Egr3 directly induced expression of suppressor of cytokine signaling-1 ( SOCS1 ) and SOCS3, inhibitors of STAT1 and STAT3, and also blocked the function of Batf , an AP-1 inhibitor , in B and T cells