Gene interactions and pathways from curated databases and text-mining

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RHOA — UTRN

Text-mined interactions from Literome

Bonet-Kerrache et al., Biochem J 2005 : We report in the present study that the active form of RhoA increases the expression of utrophin , the autosomal homologue of dystrophin in the mouse C2C12 and rat L8 myoblastic cell lines ... Even though this RhoA dependent utrophin increase is higher in proliferating myoblasts, it is maintained during myogenic differentiation ... In addition, RhoA increases plasma-membrane localization of utrophin
Gauthier-Rouvière et al., Biochem Biophys Res Commun 2009 (Muscular Dystrophy, Duchenne) : RhoA leads to up-regulation and relocalization of utrophin in muscle fibers ... We have previously demonstrated that the active form of RhoA ( RhoAV14 ) increases the expression of utrophin and its localization at the plasma membrane in cultured myoblasts