◀ Back to RHOA
RHOA — UTRN
Text-mined interactions from Literome
Bonet-Kerrache et al., Biochem J 2005
:
We report in the present study that the active form of
RhoA increases the expression of
utrophin , the autosomal homologue of dystrophin in the mouse C2C12 and rat L8 myoblastic cell lines ... Even though this
RhoA dependent
utrophin increase is higher in proliferating myoblasts, it is maintained during myogenic differentiation ... In addition,
RhoA increases plasma-membrane localization of
utrophin
Gauthier-Rouvière et al., Biochem Biophys Res Commun 2009
(Muscular Dystrophy, Duchenne) :
RhoA leads to up-regulation and relocalization of
utrophin in muscle fibers ... We have previously demonstrated that the active form of
RhoA ( RhoAV14 )
increases the expression of
utrophin and its localization at the plasma membrane in cultured myoblasts