Gene interactions and pathways from curated databases and text-mining

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ANG — NOS2

Text-mined interactions from Literome

Schultz et al., Am J Physiol Heart Circ Physiol 2002 (Arrhythmias, Cardiac...) : LV angiotensin II (ANG II) levels were increased ( 68 +/- 12 vs. 20 +/- 5 pg/g, P < 0.01 ) as steady-state ANG II type 1 ( AT(1) ) receptor mRNA was decreased 40 % and endothelial nitric oxide synthase mRNA levels were increased 2.5-fold in PO versus control dogs ( P < 0.05 )
Tian et al., Am J Physiol Heart Circ Physiol 2003 : Here, we provide evidence that angiotensin II (ANG II) significantly attenuated IL-1beta induced iNOS expression and NO production in CFbs while simultaneously decreasing apoptotic frequency
Costa et al., Am J Physiol Heart Circ Physiol 2010 (Disease Models, Animal...) : Since many ANG- ( 1-7 ) actions are enhanced in situations of increased ANG II activity, as in hypertension, in this study we investigated the in vivo effect of ANG- ( 1-7 ) on NOS activity and expression of endothelial ( eNOS ), neuronal ( nNOS ), and inducible NOS (iNOS) in ventricles from spontaneously hypertensive rats ( SHR )
Bhandari et al., Am J Respir Cell Mol Biol 2012 (Hyperoxia...) : They also demonstrate that this response is mediated, at least in part, by the ability of NOS2 to inhibit hyperoxia induced Ang2 production and thereby decrease Ang2 induced tissue injury
Yanagisawa et al., Toxicol Appl Pharmacol 1998 (Acute Kidney Injury...) : To elucidate the mechanisms underlying the development of HgCl2 induced acute renal failure ( ARF ), we examined the expression of endothelin (ET)-1, endothelial ( e ) nitric oxide synthase (NOS) and inducible ( i) NOS , and a role of angiotensin II (ANG II) and tumor necrosis factor (TNF) in glomeruli and cortices from rats at 20 h after exposure of HgCl2. Prepro-ET-1 and iNOS mRNA were significantly increased in glomeruli and cortices from rats with HgCl2 induced ARF