Gene interactions and pathways from curated databases and text-mining

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FOXP3 — HBZ

Text-mined interactions from Literome

Satou et al., PLoS Pathog 2011 (Cell Transformation, Viral...) : As a mechanism of increased T ( reg ) cells, HBZ expression directly induced Foxp3 gene transcription in T cells
Zhao et al., Blood 2011 (HTLV-I Infections...) : Finally, HBZ expression resulted in enhanced transcription of Pdgfb, Sox4, Ctgf, Foxp3 , Runx1, and Tsc22d1 genes and suppression of the Id2 gene ; such effects were similar to those by TGF-ß ... In particular, HBZ induced Foxp3 expression in naive T cells through Smad3 dependent TGF-ß signaling