Gene interactions and pathways from curated databases and text-mining

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CDC42 — FRG1

Text-mined interactions from Literome

Fukuyama et al., J Biol Chem 2005 : These results indicate that Rap1 is activated by nectins through the c-Src-Crk-C3G signaling and involved in the nectin induced, c-Src- and FRG mediated activation of Cdc42 and formation of AJs
Sato et al., Cancer Sci 2005 : The activation of Cdc42 and Rac by the trans-interaction of nectin and nectin is mediated by c-Src, another small G protein, Rap1, a Cdc42-GEF, FRG , and a Rac-GEF, Vav2
Murata et al., J Neurosci 2006 : These results indicate that CD47 promotes development of dendrites and axons in hippocampal neurons in a manner dependent, at least in part, on activation of Cdc42 and Rac mediated by Src as well as by FRG and Vav2