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RABEPK — TNF

Text-mined interactions from Literome

Wilkin et al., Eur J Immunol 2002 : We observed that ATPgammaS potentiated the IL-12p40 release induced by TNF-alpha , but also by lipopolysaccharides (LPS) and soluble CD40 ligand ( sCD40L )
Jana et al., J Neurochem 2003 : Activation of NF-kappaB as well as C/EBPbeta by p40 and inhibition of p40 induced expression of TNF-alpha by Deltap65, a dominant negative mutant of p65, and DeltaC/EBPbeta, a dominant negative mutant of C/EBPbeta, suggests that p40 induces the expression of TNF-alpha through the activation of NF-kappaB and C/EBPbeta ... Interestingly, PD98059, an inhibitor of ERK, inhibited p40 induced expression of TNF-alpha through the inhibition of C/EBPbeta, but not that of NF-kappaB, whereas SB203580, an inhibitor of p38 MAPK, inhibited p40 induced expression of TNF-alpha through the inhibition of both NF-kappaB and C/EBPbeta
Enríquez-de-Salamanca et al., Cytokine 2008 (Conjunctivitis, Allergic...) : TNF-alpha stimulated secretion of IL-12p40 was significantly increased by 30 min ; GM-CSF, MCP-1, IL-6, IL-7, IL-8, and RANTES were significantly increased by 2 h, and IFN-gamma and IL-1alpha by 24 h
Heinzel et al., J Immunol 1996 (Endotoxemia) : Pretreatment of IFN-gamma 0/0 mice with recombinant mouse IFN-gamma ( rIFN-gamma ) enhanced circulating TNF-alpha by as much as sixfold, but serum IL-12 p40 and IL-12 p70 responses increased by only twofold or less