◀ Back to TNF
PRKCB — TNF
Text-mined interactions from Literome
Dieter et al., Cell Signal 2000
(Leukemia, Monocytic, Acute) :
These results suggest that : ( 1 ) PKC-alpha but not PKC-beta is involved in the release of superoxide and PGE ( 2 ) ; ( 2 )
TNF-alpha release and the phagocytosis of latex particles are
mediated by PKC-alpha,
PKC-beta , and other PKC isoenzymes ; and ( 3 ) PKC-alpha and PKC-beta play antagonistic roles in the differentiation process of THP-1 cells
Radeff et al., Exp Cell Res 2001
(Bone Resorption) :
PTH, tumor necrosis factor-alpha
(TNF-alpha) , and interleukin-1 beta (IL-1 beta)
induced translocation of
PKC-alpha and -beta ( I ) to the plasma membrane in UMR-106 cells within 5 min ... The
stimulation of
PKC-beta ( I ) translocation by PTH,
TNF-alpha or IL-1 beta was inhibited by LY379196
Aksoy et al., Eur J Immunol 2002
:
Inhibition of LPS induced PKC activity using pseudosubstrate peptides specific for PKC isoforms established that PKC epsilon but not
PKC alpha/beta was
involved in the production of IL-12 and
TNF-alpha
Ramana et al., Endocrinology 2007
:
High glucose ( HG ) -induced
TNF-alpha release was specifically
inhibited by protein kinase C (PKC)-delta inhibitor ( Rottlerin ; EMD Biosciences, San Diego, CA ), but not
PKC-beta2 inhibitor ( CGP53353 ; Tocris Cookson Inc., Ellisville, MO ), indicating the possible involvement of PKC-delta in HG signaling