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ANG — TP53
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Viola et al., Toxicol Appl Pharmacol 2008
:
Furthermore, treatment of NCTC-2544 resulted in
p53 activation by 5-MOP, 8-MOP, and
ANG but not TMA and its phosphorylation at serine-15
Kim et al., J Biol Chem 2011
:
A marked increase in the levels of
p53 and p21
induced by
Ang II was blunted by the treatment with GW501516
Sadagopan et al., Oncogene 2012
:
Angiogenin expression
resulted in the inhibition of
p53 phosphorylation, increased p53-Mdm2 interaction, and consequently increased ubiquitination of p53
Paudel et al., J Virol 2012
:
Silencing
ANG or inhibiting its nuclear translocation
resulted in decreased nuclear LANA-1 and ANG levels, decreased interactions between ANG-LANA-1, ANG-p53, and LANA-1-p53, the induction of
p53 , p21, and Bax proteins, the increased cytoplasmic localization of p53, the downregulation of Bcl-2, the increased cleavage of caspase-3, and the apoptosis of cells