Gene interactions and pathways from curated databases and text-mining

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IFNG — SST

Text-mined interactions from Literome

Weinstock et al., Eur J Endocrinol 2000 (Granuloma...) : Somatostatin can suppress IFN-gamma secretion from T cells via interaction with the SSTR2 receptor expressed on these cells
Kang et al., Regul Pept 2001 : Recent studies have shown that somatostatin (SOM) inhibits interleukin 6 (IL-6) and interferon gamma (IFNgamma) production by lymphocytes and peritoneal macrophages, whereas substance P ( SP ) enhances these cytokines production
Muscettola et al., Immunobiology 1990 : Somatostatin and vasoactive intestinal peptide reduce interferon gamma production by human peripheral blood mononuclear cells ... In this study, we describe the effect of somatostatin (SOM) and vasoactive intestinal peptide (VIP) on interferon gamma (IFN-gamma) production by normal human peripheral blood mononuclear cells ( PBMC ) stimulated in vitro with polyclonal T cell activator staphylococcal enterotoxin A (SEA)
Elliott et al., J Immunol 1994 (Granuloma...) : It is probable that the lymphocyte SSTR2 receptor mediates somatostatin induced modulation of IFN-gamma secretion