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IL10 — PAM

Text-mined interactions from Literome

Hirata et al., Mol Immunol 2008 : However, Pam3CSK4 synergistically enhanced upLPS induced DC production of IL-10 but neither IL-12 p40 nor TNF-alpha
Lombardi et al., Clin Exp Allergy 2008 (Asthma...) : Among the three TLR2 ligands tested, the synthetic lipopeptide Pam3CSK4 is the most potent inducer of IL-12p35 and IL-10 gene expression in murine bone marrow derived DCs, as well as in purified oral myeloid DCs
Funderburg et al., Immunology 2011 : Monocytes incubated with hBD-3 or Pam ( 3 ) CSK ( 4 ) produced interleukin-6 (IL-6), IL-8 and IL-1ß, but only Pam ( 3 ) CSK ( 4 ) induced IL-10
Tan et al., Mol Pharm 2012 (Inflammation...) : In this study, we demonstrate that the Toll-like receptor-2 agonist Pam2Cys , when administered intranasally, triggers a cascade of inflammatory and innate immune signals, acting as an immunostimulant by attracting neutrophils and macrophages and inducing secretion of IL-2, IL-6, IL-10 , IFN-?, MCP-1 and TNF-a
Frei et al., J Allergy Clin Immunol 2013 (Inflammation) : Histamine suppressed MDDC chemokine and proinflammatory cytokine secretion, nuclear factor ?B and activator protein 1 activation, mitogen activated protein kinase phosphorylation, and TH1 polarization of naive lymphocytes, whereas IL-10 secretion was enhanced in response to LPS and Pam3Cys