◀ Back to TRAF6

IL18 — TRAF6

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: TRAF6 → IL18 (increases, IL18 Activity)
  Evidence: Ariadne: Upon binding to its receptors, IL-18 induces activation of IL-1 receptor-associated kinase and TNF receptor-associated factor-6 (TRAF-6) and nuclear translocation of nuclear factor kappa-B (NFkappa-B) ( 13 , 14 ). [Regulation]

Text-mined interactions from Literome

Lomaga et al., Genes Dev 1999 (Osteopetrosis) : TRAF6 deficiency results in osteopetrosis and defective interleukin-1 , CD40, and LPS signaling
Mason et al., Infect Immun 2004 : TRAF6 dependent mitogen activated protein kinase activation differentially regulates the production of interleukin-12 by macrophages in response to Toxoplasma gondii
Frobøse et al., Mol Endocrinol 2006 : Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex