Gene interactions and pathways from curated databases and text-mining

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PDLIM7 — TBX5

Text-mined interactions from Literome

Tang et al., J Biol Chem 2003 : HOS did not regulate stability of LMP1-95-8 unless it was mutated to bear additional lysine residues near the cryptic motif
Camarata et al., Dev Biol 2010 : Pdlim7 ( LMP4 ) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation ... We show that Pdlim7/Tbx5 interactions affect the expression of Tbx5 target genes nppa and tbx2b at the AV boundary, and their domains of misexpression directly correlate with the identified valve defects
Camarata et al., BMC developmental biology 2010 : Recent findings have revealed that Tbx5 transcriptional activity is regulated by dynamic nucleocytoplasmic shuttling and interaction with Pdlim7 , a PDZ-LIM protein family member, along actin filaments ... By controlling Tbx5 subcellular localization and transcriptional activity and possibly additional yet unknown means, Pdlim7 is required for proper development of the heart and the fins