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GYS2 — IL6

Text-mined interactions from Literome

Beurel et al., J Immunol 2011 (Encephalomyelitis, Autoimmune, Experimental...) : During polarization of CD4 ( + ) T cells to Th17 cells, we found that inhibition of glycogen synthase kinase-3 ( GSK3 ) blocked IL-6 production, STAT3 activation, and polarization to Th17 cells
Wang et al., J Cell Biochem 2012 : We showed that IL-6 activated Akt and inhibited glycogen synthase kinase-3ß ( GSK-3ß ) , highly associating with fascin-1 mRNA expression
Kanemaki et al., Hepatology 1998 : Furthermore, it was discovered that IL-1beta and IL-6 inhibited glycogen synthase activity and, in contrast, accelerated glycogen phosphorylase activity ... In experiments with kinase inhibitors, serine/threonine kinase inhibitor K252a blocked IL-1beta- and IL-6 induced inhibitions of glycogen deposition, as well as glycogen synthase activity, whereas another kinase inhibitor staurosporine blocked only IL-6 induced inhibition