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IL6 — POU5F1

Text-mined interactions from Literome

Bao et al., PloS one 2012 (Neoplasm Invasiveness...) : The treatment of PCa cells with CDF, a novel Curcumin derived synthetic analogue previously showed anti-tumor activity in vivo, inhibited the productions of VEGF and IL-6 , and down-regulated the expression of Nanog, Oct4 , EZH2 mRNAs, as well as miR-21 under hypoxic condition
Kim et al., Cell Signal 2013 (Breast Neoplasms...) : IL-6 regulates CSC associated OCT-4 gene expression through the IL-6-JAK1-STAT3 signal transduction pathway in non-CSCs. Inhibiting this pathway by treatment with anti-IL-6 antibody ( 1µg/ml ) or niclosamide ( 0.5-2µM ) /LLL12 ( 5-10µM ) effectively prevented OCT-4 gene expression