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CDK4 — MAPK8

Text-mined interactions from Literome

Liu et al., Di Yi Jun Yi Da Xue Xue Bao 2002 (Cardiomyopathy, Hypertrophic...) : [ Regulation of cyclin dependent kinase inhibitors by mitogen activated protein kinase in angiotensin II-stimulated vascular smooth muscle cell hypertrophy ] ... To investigate the role of mitogen activated protein kinase ( MAPK ) in the regulation of cyclin dependent kinase inhibitors ( CDKI ) in the process of vascular smooth muscle cell ( VSMC ) hypertrophy induced by angiotensin II stimulation
Lee et al., J Cell Biochem 2006 : In addition, PD 98059 ( a MEK inhibitor ), SB 203580 ( a p38 MAPK inhibitor ), and SP 600125 ( a JNK inhibitor ) blocked the EGF induced stimulation of [ 3H ] -thymidine incorporation and CDK-2/4 expression
Benson et al., Blood 2009 (MAP Kinase Signaling System) : The effect results at least in part via enhanced MAPK mediated modulation of p27 and CDK4
Brennan et al., J Med Food 2012 (Adrenocortical Carcinoma) : BME treatment enhanced cellular tumor antigen p53, cyclin dependent kinase inhibitor 1A ( also called p21 ), and cyclic AMP dependent transcription factor-3 levels and inhibited G1/S-specific cyclin D1, D2, and D3, and mitogen activated protein kinase 8 ( also called Janus kinase ) expression, suggesting an additional mechanism involving cell cycle regulation and cell survival