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IL1A — TAB1

Text-mined interactions from Literome

Takaesu et al., Mol Cell Biol 2001 (MAP Kinase Signaling System) : We show that IL-1 stimulation induces the rapid but transient association of IRAK, TRAF6, TAB2 , and TAK1 ... We show that IL-1 stimulation induces the rapid but transient association of IRAK, TRAF6, TAB2, and TAK1
Qian et al., J Biol Chem 2001 : Our results show that IRAK is required for the IL-1 induced phosphorylation of TAK1, TAB1 , and TAB2 ... Our results show that IRAK is required for the IL-1 induced phosphorylation of TAK1, TAB1 , and TAB2
McDermott et al., J Biol Chem 2002 : In addition we found a role for TAK-1 in the activation of p38 MAPK by IL-1 , with TAK-1 also associating with active Ras
Ishitani et al., EMBO J 2003 (Inflammation) : TAK1 , a MAPKKK, is critical for both IL-1- and TNF induced activation of the NF-kappaB pathway
Frobøse et al., Mol Endocrinol 2006 : Furthermore, SOCS-3 inhibited the IL-1 induced catalytic activity of TAK1
Bertelsen et al., Cell Signal 2007 : In this study, a critical role for TAK1 in IL-1alpha or TNFalpha stimulated MAPK and NFkappaB activation was confirmed by inhibition of the nuclear accumulation of NFkappaB p65 and phosphorylated forms of c-Jun and p38 following siRNA mediated TAK1 silencing ... Interestingly, IL-6, IL-8 and GM-CSF release from TAB1 siRNA transfected cells was significantly reduced following IL-1alpha treatment, but was unchanged after TNFalpha stimulation, suggesting differential roles for TAB1 in IL-1alpha and TNFalpha signalling pathways
Mendoza et al., Biochem J 2008 : Roles for TAB1 in regulating the IL-1 dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex
Xiao et al., J Biol Chem 2008 : Importantly, the negative impact of Pellino 3b on IL-1 induced IRAK degradation correlated with the inhibitory effect of Pellino 3b on the IL-1 induced TAK1 dependent pathway, suggesting that a positive role of IRAK degradation in IL-1 induced TAK1 activation
Geurts et al., Rheumatology (Oxford) 2011 (Arthritis, Rheumatoid) : In synovial fibroblasts, TAK1 regulated IL-1 and TNF mediated NF-?B, but not Saa3-promoter reporter activation
Cui et al., Mol Cell Biol 2012 : Taken together, these results implicate a positive role of ß-TrCP mediated IRAK1 degradation in IL-1 induced TAK1 activation
Stockert et al., PloS one 2013 : PPARß/d enhances the interaction between TAK1 and the small heat-shock protein HSP27, a known positive modulator of TAK1 mediated IL-1ß signaling