Gene interactions and pathways from curated databases and text-mining

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NFKBIA — VEGFA

Text-mined interactions from Literome

Kiriakidis et al., J Cell Sci 2003 (Inflammation...) : VEGF expression in human macrophages is NF-kappaB dependent : studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2
Xu et al., Oncogene 2005 (Prostatic Neoplasms) : Analogous to treatments with SFN and PEITC, SR-IkappaBalpha also strongly inhibited NF-kappaB transcriptional activity as well as VEGF , cylcin D1, and Bcl-X ( L ) expression
Tong et al., Respir Res 2006 : In addition, HIMF strongly induced Akt phosphorylation, and suppression of Akt activation by specific inhibitors and dominant negative mutants for PI-3K, and IKK or IkappaBalpha blocked HIMF induced NF-kappaB activation and attenuated HIMF induced VEGF production