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EPHB2 — MAP3K11
Text-mined interactions from Literome
Chadee et al., Nat Cell Biol 2004
:
MLK3 is
required for mitogen activation of B-Raf,
ERK and cell proliferation ... Our results define an unexpected
role for
MLK3 in mitogen regulation of B-Raf,
ERK and cell proliferation
Chadee et al., Cell cycle (Georgetown, Tex.) 2004
:
These results define a new
role for
MLK3 in B-Raf activation,
ERK signaling and cell proliferation
Chadee et al., Proc Natl Acad Sci U S A 2006
:
We show that the activation of
ERK and the proliferation of human schwannoma cells bearing a loss-of-function mutation in the neurofibromatosis 2 (NF2) gene
require MLK3 ... Thus,
MLK3 is part of a multiprotein complex and is
required for
ERK activation
Hebron et al., Br J Haematol 2013
(Multiple Myeloma...) :
In myeloma tumour cells,
MAP3K8 acts as mitogen induced MAP3K in mitosis and is
required for TNFa mediated
ERK activation