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ANGPT2 — PI3

Text-mined interactions from Literome

Takahashi et al., Am J Physiol 1999 : ANG II-stimulated Akt/PKB activation was inhibited by the tyrosine kinase inhibitors genistein and herbimycin A and by the phosphatidylinositol 3-kinase (PI3K) inhibitors wortmannin and LY-294002
Song et al., Mech Dev 2010 : E12.5 mice metanephroi were grown for 24h in the presence or absence of Ang II , Ang II AT(1) receptor ( AT(1)R ) antagonist candesartan, phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 or ERK1/2 inhibitor PD98059
Pu et al., Am J Physiol Heart Circ Physiol 2011 : Both insulin and ANG II induced the upregulation of phosphatidyl inositol 3-kinase (PI3K)-d by two- to threefold ( P < 0.05 ), and this effect was both necessary and sufficient to uncover NO-induced motogenesis