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IL2 — JUNB
Text-mined interactions from Literome
Wang et al., J Neuroimmunol 2000
:
The neuropeptides VIP and PACAP
inhibit IL-2 transcription by decreasing c-Jun and increasing
JunB expression in T cells
Garaude et al., J Immunol 2008
:
JunB is a transcriptional
activator of various cytokine genes, such as
IL-2 , IL-4, and IL-10 ; however, the post-translational modifications that regulate JunB activity in T cells are poorly characterized ... Ectopic expression of
JunB in activated human primary CD4 ( + ) T cells
induced activation of the endogenous
IL-2 promoter, whereas the nonsumoylable JunB mutant did not
Azzoni et al., J Immunol 1998
:
We previously demonstrated that expression of transcription factors ( e.g., Egr-1,
JunB , and c-Fos ) is differentially
regulated by
IL-2 and IL-12