Gene interactions and pathways from curated databases and text-mining

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IL2 — JUNB

Text-mined interactions from Literome

Wang et al., J Neuroimmunol 2000 : The neuropeptides VIP and PACAP inhibit IL-2 transcription by decreasing c-Jun and increasing JunB expression in T cells
Garaude et al., J Immunol 2008 : JunB is a transcriptional activator of various cytokine genes, such as IL-2 , IL-4, and IL-10 ; however, the post-translational modifications that regulate JunB activity in T cells are poorly characterized ... Ectopic expression of JunB in activated human primary CD4 ( + ) T cells induced activation of the endogenous IL-2 promoter, whereas the nonsumoylable JunB mutant did not
Azzoni et al., J Immunol 1998 : We previously demonstrated that expression of transcription factors ( e.g., Egr-1, JunB , and c-Fos ) is differentially regulated by IL-2 and IL-12