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AGTR1 — IL1A

Text-mined interactions from Literome

Wang et al., Apoptosis 2012 : Overexpression of AT1R and AT2R markedly increased IL-1ß ( AT2R > AT1R ), iNOS ( AT2R > AT1R ) and eNOS expression
Lv et al., Braz J Med Biol Res 2012 : In the PS group, TNF-a increased at 1 , 3, and 5 weeks and IL-1ß increased significantly after 1 and 3 weeks of stress, and then decreased to normal levels by 5 weeks
Kawakami et al., Arthritis 2012 : The effect of IL-1 on AT1R/AT2R expression in the chondrocytes was analyzed by quantitative PCR and flow cytometry ... Human articular chondrocytes, at least partially, express angiotensin II receptors, and IL-1 stimulation induced AT1R/AT2R mRNA expression significantly
Pignol et al., Prostaglandins 1987 : PAF-acether at 1pM increased IL1 release by 120 +/- 39 % and synthesis by 87 +/- 27 % whereas at 0.1 microM a decrease of IL1 release of 52 +/- 9 % and synthesis of 46 +/- 6 % were observed
Oberyszyn et al., Mol Carcinog 1993 (Inflammation...) : IL-1 alpha gene expression increased in epidermal tissue isolated from SENCAR mice at 1 , 3, 6, 10, 16, and 22 wk after a single treatment with 10 nmol 7,12-dimethylbenz [ a ] anthracene ( DMBA ) and subsequent twice-weekly application of 2 micrograms TPA
Sasamura et al., Hypertension 1997 : We therefore examined the effects of interleukin-1 alpha ( 220 U/mL [ 10 ng/mL ] ), tumor necrosis factor-alpha ( 280 U/mL [ 100 ng/mL ] ), and interferon gamma ( 100 U/mL ) on Ang II type 1 (AT1) receptors expressed in rat vascular smooth muscle cells ... Although the upregulation of AT1 by interleukin-1 alpha was unaffected by pretreatment of cells with N-monomethyl-L-arginine or indomethacin, downregulation of AT1 by interleukin-1 alpha combined with tumor necrosis factor-alpha/interferon gamma was inhibited by N-monomethyl-L-arginine ( P < .01 ) ... These results demonstrate that interleukin-1 alpha upregulates AT1 receptors and enhances Ang II-stimulated hypertrophic responses