Gene interactions and pathways from curated databases and text-mining

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BDNF — IL1A

Text-mined interactions from Literome

Jornot et al., Rhinology 2007 (Nasal Polyps) : On the other hand, TNFalpha, IL-1beta , and IFN-gamma did not affect DPP-IV activity but significantly increased the cellular expression and the basolateral secretion of BDNF
Lee et al., J Orthop Res 2011 (Intervertebral Disc Degeneration...) : In this study, we investigated the effects of inflammatory cytokines, IL-1ß , and TNF-a, on the expression of an angiogenic factor, vascular endothelial growth factor ( VEGF ), and neurotrophic factors, nerve growth factor (NGF) and brain derived neurotrophic factor (BDNF) , in human IVD degeneration ... IL-1ß and TNF-a stimulated the gene expression of VEGF, NGF, and BDNF in nucleus pulposus ( NP ) cells isolated from patient tissues
Tong et al., J Neurosci 2012 : IL-1ß upregulated p38 mitogen activated protein kinase ( MAPK ), and inhibiting p38 MAPK prevented IL-1ß from disrupting BDNF signaling