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BCL2 — BRCA1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
McEachern et al., J Cell Biochem 2003
:
Full length
BRCA1 transactivated the estrogen receptor-alpha (ERalpha) and
BCL2 promoters as well as AP-1, SRE, and CRE containing promoters
Laulier et al., Cancer Res 2011
:
In this study, we identified the breast cancer tumor suppressor
BRCA1 , which plays an essential role in homologous recombination ( HR ), as a
target for
Bcl-2 in the repression of HR