Richards et al., Curr Biol 1999
:
Nevertheless, activation of full-length RSK1 in the absence of serum required activation by both PDK1 and ERK ... Activation of phosphotransferase activity of full-length RSK1 in vivo requires both PDK1 and ERK
Kharebava et al., J Neurosci 2008
:
Consistent with the observations that in BDNF stimulated neurons RSK1/2 activation required both PDK1 and ERK1/2, ERK1/2 knockdown removed BDNF mediated survival