Gene interactions and pathways from curated databases and text-mining

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IL1A — TIMP2

Text-mined interactions from Literome

Kishida et al., Fetal Diagn Ther 2003 (Obstetric Labor, Premature) : The levels of interleukin (IL) 1alpha , IL-1beta, IL-6, IL-8, matrix metalloproteinase (MMP) 1, MMP-2, MMP-9, tissue inhibitors of matrix metalloproteinase ( TIMP ) 1, TIMP-2 , granulocyte elastase, and fetal fibronectin in cervical diluted specimens were measured by immunoassay, and the uterine cervix was assessed by transvaginal ultrasonography
Guo et al., Int J Cardiol 2008 : The purpose of this study was to determine the ability and possible signal pathway involved of imidaprilat, an ACE inhibitor, to modulate MMP-2 and TIMP-2 in human cardiac fibroblasts in the presence of interleukin (IL)-1beta
Turner et al., Matrix Biol 2010 : IL-1a increased expression of TIMP-1 slightly, but not TIMP-2
Hakelius et al., Anticancer Res 2013 (Carcinoma, Squamous Cell...) : Interleukin 1 alpha ( IL1a ) up-regulated both MMP1 and MMP3 and down-regulated PAI-1, TIMP2 and -3
Zeng et al., Exp Cell Res 1994 : Although Il-1 alpha had no significant effect on TIMP-2 mRNA or on expression of 72-kDa gelatinase, in either early or late passage cells, Il-1 alpha increased the level of a TIMP-2-72-kDa gelatinase complex