Gene interactions and pathways from curated databases and text-mining

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ITGB1 — YES1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: YES1 → ITGB1 (increases, ITGB1 Activity, YES1 Activity) Rüegg et al., Biochim Biophys Acta 2004*
    Evidence: In the second case, Fyn or Yes, activated by some b1 and aV integrins, recruit Shc through their SH3 domain and phosphorylates it, thus promoting Shc association with the Grb2-Sos complex [62,63].

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *